| First Author | Faure P | Year | 1994 |
| Journal | Immunology | Volume | 82 |
| Issue | 4 | Pages | 645-50 |
| PubMed ID | 7835930 | Mgi Jnum | J:20028 |
| Mgi Id | MGI:68144 | Citation | Faure P, et al. (1994) Characterization of liver lymphomyeloid cells in mice infected with Plasmodium yoelii sporozoites. Immunology 82(4):645-50 |
| abstractText | We have isolated, characterized and quantified the immunocompetent cells present in the extravascular hepatic compartment at various stages after Plasmodium yoelii malaria infection with sporozoites. Cytological analyses revealed a predominantly lymphoid population. In mice with a primary infection, the predominant cells were CD4+, CD8+ and B lymphocytes. In fully protected mice, CD3+ CD4- CD8- and polymorphonuclear cells, particularly eosinophils, were most common. The significance of changes in subpopulations is discussed in relation to antigen presentation and host-protective mechanisms. |
