Primary Identifier | MGI:2443635 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 193003 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables phosphatidylinositol bisphosphate binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and transmembrane transporter binding activity. Acts upstream of or within behavioral response to pain and response to heat. Located in plasma membrane. Is expressed in gut; nervous system; and olfactory epithelium. Orthologous to human PIRT (phosphoinositide interacting regulator of transient receptor potential channels). PHENOTYPE: Mice homozygous for a null allele exhibit decreased sensitivity to thermal and capsaicin nociception. [provided by MGI curators] |