Primary Identifier | MGI:3056737 | Allele Type | Transgenic |
Attribute String | Reporter | Gene | Tg(TF-CAT)48Gsa |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | 1196 bp of promoter sequence (-1152 to + 46) from the human TF gene were used to drive the expression of a CAT reporter gene. The transgene was expressed at high levels in the liver and brain, with brain levels being 10-fold higher than in the liver. Iron administration mice resulted in a significant decrease of transgene expression. |