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Allele : Ripk3<tm1.1Geno> receptor-interacting serine-threonine kinase 3; targeted mutation 1, Genoway

Primary Identifier  MGI:5749174 Allele Type  Targeted
Attribute String  Conditional ready Gene  Ripk3
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed exon 2 with a p.K51A mutation replaced the endogenous exon 2 and an FRT site flanked neomycin resistance gene cassette was inserted into intron 3 via homologous recombination. Flp-mediated recombination removed the neo cassette. The mutation renders the encoded peptide kinase-dead.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Rip3<K51A>,
  • Rip3<K51A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories

Trail: Allele