Primary Identifier | MGI:5749174 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Ripk3 |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A floxed exon 2 with a p.K51A mutation replaced the endogenous exon 2 and an FRT site flanked neomycin resistance gene cassette was inserted into intron 3 via homologous recombination. Flp-mediated recombination removed the neo cassette. The mutation renders the encoded peptide kinase-dead. |