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Allele : Elmo2<tm2.1Jfco> engulfment and cell motility 2; targeted mutation 2.1, Jean-Francois Cote
Primary Identifier  MGI:7544997 Allele Type  Targeted
Gene  Elmo2 Transmission  Germline
Strain of Origin  129/Sv Is Recombinase  false
Is Wild Type  false
molecularNote  The targeting construct replaced exon 7 with one containing the mutation responsible for the amino acid substitution of isoleucine to aspartic acid at position 196 (I196D). This mutation abolishes the function of the ELMO inhibitory domain. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Elmo2<EID>,
  • Elmo2<EID>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

4 Publication categories

Trail: Allele




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