Primary Identifier | IPR029852 | Type | Family |
Short Name | Na/Pi_transpt_2B |
description | Sodium-dependent phosphate transporter type 2B (also known as SLC34A2) may be the main phosphate transport protein in the intestinal brush border membrane [, ]. It is also expressed in lung []. Mutations in the SLC34A2 cause pulmonary alveolar microlithiasis, a rare disease characterised by the deposition of calcium phosphate microliths throughout the lungs []. Loss function of SLC34A2 in adult mice cause pulmonary calcification and reduced intestinal phosphate absorption []. |