Primary Identifier | MGI:2680581 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Nod2 |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The start codon, first CARD domain and half of the second CARD domain were eliminated by replacing the first exon with a PGK-neomycin resistance gene. RT-PCR on macrophage extracts demonstrated the absence of gene transcript. |