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Allele : Nod2<tm1Pmu> nucleotide-binding oligomerization domain containing 2; targeted mutation 1, Peter J Murray

Primary Identifier  MGI:2680581 Allele Type  Targeted
Attribute String  Null/knockout Gene  Nod2
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  The start codon, first CARD domain and half of the second CARD domain were eliminated by replacing the first exon with a PGK-neomycin resistance gene. RT-PCR on macrophage extracts demonstrated the absence of gene transcript.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Nod2<->,
  • Nod2<->,
  • Card15<->,
  • Card15<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

16 Publication categories

Trail: Allele