| Primary Identifier | MGI:1919156 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 268721 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Involved in positive regulation of miRNA catabolic process. Located in cytosol. Part of cullin-RING ubiquitin ligase complex. Is expressed in central nervous system and retina. Orthologous to human ZSWIM8 (zinc finger SWIM-type containing 8). PHENOTYPE: Homozygous null mice exhibit perinatal lethality, cyanosis, respiratory distress, decreased fetal and neonatal size, a lung sacculation defect due to failed maturation of alveolar epithelial cells, and ventricular septal defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
