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Allele : Eng<tm1Hma> endoglin; targeted mutation 1, Helen M Arthur

Primary Identifier  MGI:2177822 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Eng
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An HA tag followed by a stop codon was introduced into exon 8, and was followed by an IRES-lacZ gene and neomycin selection cassette that replaced exons 9, 10 and 11. Western blot analysis on homozygous embryos demonstrated that no detectable ENG protein was expressed from this allele; however, a beta-galactosidase protein was expressed under the control of the endogenous promoter.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Eng<->,
  • Eng<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

18 Publication categories

Trail: Allele