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Protein Domain : Histone-lysine N-methyltransferase 2D

Primary Identifier  IPR037890 Type  Family
Short Name  KMT2D
description  Histone-lysine N-methyltransferase 2D (KMT2D, also known as MLL2; ) is a catalytic component of the MLL2/3 complex (also named ASCOM complex) []and methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. KMT2D is recruited by ESR1 and acts as a coactivator of the oestrogen receptor alpha [].
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Trail: ProteinDomain




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