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Allele : Krt14<tm1Der> keratin 14; targeted mutation 1, Dennis R Roop

Primary Identifier  MGI:2653126 Allele Type  Targeted
Attribute String  Not Specified Gene  Krt14
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A C to T point mutation at codon 131 was introduced to the gene and a floxed PGK-neo cassette was inserted into the downstream exon via homologous recombination. The point mutation results in an arginine to cysteine substitution. The targeted allele was confirmed by Southern blot and sequence analysis.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • mtK14<neo>,
  • mut<neo>,
  • mut<neo>,
  • mtK14<neo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele