Primary Identifier | MGI:5527387 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Bok |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted upstream of exon 1b. An FRT- and loxP-flanked hygromycin resistance cassette was inserted downstream of exon 2. Cre-mediated recombination removed exon 1b, exon 2 and the hygromycin resistance cassette. Western blot analysis confirmed the absence of protein expression in the uterus, rectum, colon, placenta and spleen. |