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Publication : Cloning and expression of a glutamate transporter from mouse brain.

First Author  Tanaka K Year  1993
Journal  Neurosci Lett Volume  159
Issue  1-2 Pages  183-6
PubMed ID  7903437 Mgi Jnum  J:16962
Mgi Id  MGI:65019 Doi  10.1016/0304-3940(93)90829-a
Citation  Tanaka K (1993) Cloning and expression of a glutamate transporter from mouse brain. Neurosci Lett 159(1-2):183-6
abstractText  A complementary DNA clone encoding a transporter for glutamate has been isolated from mouse brain, and its functional properties have been examined in Xenopus oocytes. The transporter displays high affinity for glutamate (Km = 72 microM) and is dependent on external Na+. The cDNA sequence predicts a protein of 543 amino acids with 6 potential transmembrane domains. Northern blot analysis indicates the mRNA encoding the glutamate transporter is expressed both in the brain and in peripheral tissues.
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