First Author | Tanaka K | Year | 1993 |
Journal | Neurosci Lett | Volume | 159 |
Issue | 1-2 | Pages | 183-6 |
PubMed ID | 7903437 | Mgi Jnum | J:16962 |
Mgi Id | MGI:65019 | Doi | 10.1016/0304-3940(93)90829-a |
Citation | Tanaka K (1993) Cloning and expression of a glutamate transporter from mouse brain. Neurosci Lett 159(1-2):183-6 |
abstractText | A complementary DNA clone encoding a transporter for glutamate has been isolated from mouse brain, and its functional properties have been examined in Xenopus oocytes. The transporter displays high affinity for glutamate (Km = 72 microM) and is dependent on external Na+. The cDNA sequence predicts a protein of 543 amino acids with 6 potential transmembrane domains. Northern blot analysis indicates the mRNA encoding the glutamate transporter is expressed both in the brain and in peripheral tissues. |