| Primary Identifier | MGI:1929501 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 65106 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable transmembrane transporter binding activity. Involved in negative regulation of L-glutamate import across plasma membrane. Acts upstream of or within with a negative effect on L-glutamate import across plasma membrane and protein localization to plasma membrane. Acts upstream of or within several processes, including L-glutamate transmembrane transport; cellular response to oxidative stress; and glutathione metabolic process. Is active in plasma membrane and presynaptic cytosol. Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human ARL6IP5 (ADP ribosylation factor like GTPase 6 interacting protein 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased resistance to oxidative stress hypoactivity, enhanced motor coordination and learning, and enhanced spatial working memory. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
