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Protein Coding Gene : Trim58 tripartite motif-containing 58

Primary Identifier  MGI:2684862 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  216781
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables dynein heavy chain binding activity; dynein intermediate chain binding activity; and ubiquitin protein ligase activity. Involved in several processes, including positive regulation of erythrocyte enucleation; protein ubiquitination; and regulation of nuclear migration along microtubule. Predicted to be active in cytosol and nucleoplasm. Orthologous to human TRIM58 (tripartite motif containing 58).
PHENOTYPE: Homozygous null mice exhibit no overt phenotype but show delayed resolution of DSS-induced colitis. [provided by MGI curators]
  • synonyms:
  • gene model 1783, (NCBI),
  • LOC386443,
  • LOC216781,
  • tripartite motif-containing 58,
  • MGI:2686629,
  • Trim58,
  • gene model 16, (NCBI),
  • Gm1783,
  • Gm16

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Genome

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0 Canonical

0 CDSs

0 Exons

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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

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Disease

Mouse features --> Human diseases

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