Primary Identifier | MGI:2677669 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence | Gene | Gabrb2 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A mutation was introduced into exon 8 changing the codon for asparagine at amino acid position 265 into one for serine (N265S) at the same time that a floxed neomycin resistance cassette was inserted into intron 7. The neomycin gene was subsequently removed by cre-mediated excision. This mutation does not change the expression level of this receptor subunit. |