Primary Identifier | MGI:88547 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 13000 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables protein serine/threonine kinase activity. Acts upstream of or within regulation of cell cycle and spermatogenesis. Predicted to be located in acrosomal vesicle. Predicted to be part of PcG protein complex; chromatin; and protein kinase CK2 complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study male infertility. Orthologous to human CSNK2A2 (casein kinase 2 alpha 2). PHENOTYPE: Males homozygotes for a targeted null mutation of the minor catalytic subunit exhibit infertility with oligospermia and abnormally shaped spermatid nuclei. [provided by MGI curators] |