|  Help  |  About  |  Contact Us

Comment :

Type  MGI:General Description  unlike in wild-type mice, no increase in field excitatory postsynaptic potential (fEPSP) is observed under a protocol designed to evoke modest, subsaturating long term potentiation under a protocol designed to produce saturating long term potentiation, mice fail to exhibit a decrease in fEPSP during the first time point compared with similarly treated wild-type mice under a long term depression protocol, fEPSP slopes fail to decrease as in similarly treated wild-type mice under a long term depression protocol with DL-AP-5 co-application with glutamate transporter inhibitor L-trans-pyrrolidine-2,4-dicarboxylic acid (tPDC), mice exhibit an increase in the fEPSC slope unlike in wild-type mice and an AP-5 washout with another round of stimulation does not produce a lasting decrease in fEPSP slope as observed in similarly treated wild-type mice