Primary Identifier | MGI:1889679 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 58807 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable bile acid transmembrane transporter activity; sodium-independent organic anion transmembrane transporter activity; and thyroid hormone transmembrane transporter activity. Predicted to be involved in several processes, including organic anion transport; positive regulation of thyroid hormone generation; and thyroid hormone transport. Predicted to act upstream of or within lipid transport and monoatomic ion transport. Located in basolateral plasma membrane. Is expressed in blood vessel; central nervous system; cochlea; and retina. Orthologous to human SLCO1C1 (solute carrier organic anion transporter family member 1C1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased thyroxine and triiodothyronine levels in the forebrain, in the absence of overt growth, reproductive or neurological abnormalities. [provided by MGI curators] |