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Protein Coding Gene : Pou3f1 POU domain, class 3, transcription factor 1

Primary Identifier  MGI:101896 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  18991
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables DNA binding activity. Involved in positive regulation of DNA-templated transcription and positive regulation of gene expression. Acts upstream of or within forebrain development; keratinocyte differentiation; and myelination in peripheral nervous system. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; early conceptus; nervous system; sensory organ; and urinary system. Orthologous to human POU3F1 (POU class 3 homeobox 1).
PHENOTYPE: Homozygotes for targeted null mutations exhibit cyanosis and respiratory distress at birth and defective peripheral myelination due to arrested Scwann cell maturation. Mutants usually die at birth or shortly thereafter. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-15280,
  • Oct-6,
  • MGD-MRK-18723,
  • Oct6,
  • Pou3f1,
  • Tst1,
  • Tst-1,
  • POU domain, class 3, transcription factor 1,
  • Test1,
  • MGD-MRK-13081,
  • testes 1,
  • Otf6,
  • MGD-MRK-15042,
  • octamer binding transcription factor 6,
  • Scip

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For