| Primary Identifier | IPR038216 | Type | Homologous_superfamily |
| Short Name | SATB_CUTL_sf |
| description | This superfamily represents a domain found in SATB (special AT-rich sequence-binding) proteins that are global chromatin organisers and gene expression regulators essential for T-cell development and breast cancer tumour growth and metastasis. The N terminus of SATB1 (residues 90-204) is made up of ULD and CUTL domains. This entry represents the CUTL (CUT repeat-like) domain, which shares structure similarity with the CUT1 domain and has the evolutionarily conserved amino acids involved in CUT1 DNA binding [, ]. This domain is essential for the contact between DNA and SATB1. |
