| Primary Identifier | MGI:893573 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 22264 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables triglyceride binding activity. Involved in several processes, including cellular response to X-ray; positive regulation of intestinal lipid absorption; and positive regulation of lipid transport. Located in endoplasmic reticulum and extracellular region. Is expressed in several structures, including female reproductive system; intestine; and lower jaw. Orthologous to human PRAP1 (proline rich acidic protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit an increased serum IgG2a response to ovalbumin challenge, increased serum immunoglobulin and cytokine levels, altered microbiota in the small intestine, and increased mortality and enterocyte apoptosis in response to ionizing radiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
