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Protein Coding Gene : Slc24a5 solute carrier family 24, member 5
Primary Identifier  MGI:2677271 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  317750
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables calcium ion transmembrane transporter activity. Involved in calcium ion import. Acts upstream of or within negative regulation of melanin biosynthetic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in trans-Golgi network. Is expressed in several structures, including adrenal gland; brain; gonad; sensory organ; and submandibular gland. Used to study ocular albinism 1. Human ortholog(s) of this gene implicated in oculocutaneous albinism type VI. Orthologous to human SLC24A5 (solute carrier family 24 member 5).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit hypopigmentation and ocular albinism. [provided by MGI curators]
  • synonyms:
  • NCX5,
  • solute carrier family 24, member 5,
  • RIKEN cDNA F630045L20 gene,
  • Slc24a5,
  • NCKX5,
  • Oca6,
  • F630045L20Rik
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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