| First Author | Lazo PS | Year | 1992 |
| Journal | Nucleic Acids Res | Volume | 20 |
| Issue | 2 | Pages | 343-50 |
| PubMed ID | 1741260 | Mgi Jnum | J:2957 |
| Mgi Id | MGI:51473 | Doi | 10.1093/nar/20.2.343 |
| Citation | Lazo PS, et al. (1992) Structure and mapping of the fosB gene. FosB downregulates the activity of the fosB promoter. Nucleic Acids Res 20(2):343-50 |
| abstractText | We have determined the genomic structure of the fosB gene and shown that it consists of 4 exons and 3 introns at positions also found in the c-fos gene. By deletion analysis we have characterized a region upstream of the TATA box which is the promoter region of the gene. Several consensus sequences have been identified, including an SRE and AP-1 binding site whose relative positions are identical to those in the 5' upstream region of the c-fos gene. We have also shown that FosB and c-Fos can downregulate the activity of the fosB promoter to a similar extent. The fosB gene is located in the [A1-B1] region of mouse chromosome 7. |
