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Protein Coding Gene : Cysltr1 cysteinyl leukotriene receptor 1
Primary Identifier  MGI:1926218 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  58861
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables leukotriene receptor activity. Acts upstream of or within several processes, including calcium ion transport; chemotaxis; and inflammatory response to antigenic stimulus. Located in plasma membrane. Is expressed in central nervous system and retina. Human ortholog(s) of this gene implicated in allergic disease; asthma; and rhinitis. Orthologous to human CYSLTR1 (cysteinyl leukotriene receptor 1).
PHENOTYPE: Mice homozygous for disruptions in this gen develop normally and both sexes are fertile. However, they display abnormalities in vascular permeability associated with inflammation. [provided by MGI curators]
  • synonyms:
  • expressed sequence BB147369,
  • cysteinyl leukotriene 1 receptor,
  • CysLT1R,
  • cysteinyl leukotriene receptor 1,
  • leukotriene D4 receptor,
  • MGI:2148041,
  • BB147369,
  • Cysltr1
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Trail: ProteinCodingGene

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