| Primary Identifier | MGI:2146616 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 106389 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable transcription elongation factor activity. Acts upstream of or within negative regulation of cell growth; negative regulation of epithelial cell proliferation involved in prostate gland development; and positive regulation of DNA-templated transcription. Located in nucleoplasm. Is expressed in several structures, including genitourinary system; integumental system; nervous system; sensory organ; and tooth. Orthologous to human EAF2 (ELL associated factor 2). PHENOTYPE: Mice homozygous for a null allele exhibit premature death, enlarged heart and prostate associated with hypertrophy, increased tumor incidence, prostate inflammation and an increased prostatic intraepithelial neoplasia incidence. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
