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Protein Coding Gene : Cep55 centrosomal protein 55

Primary Identifier  MGI:1921357 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  74107
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable identical protein binding activity. Predicted to be involved in cranial skeletal system development; establishment of protein localization; and midbody abscission. Predicted to act upstream of or within cell division. Located in intercellular bridge and midbody. Is expressed in germ cell of testis and ovary. Human ortholog(s) of this gene implicated in multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly. Orthologous to human CEP55 (centrosomal protein 55).
PHENOTYPE: Mice homozygous for a null allele exhibit impaired cytokinesis in neural progenitor cells with postnatal lethality, microcephaly, decreased weight, pallor, and abnormal kidneys. [provided by MGI curators]
  • synonyms:
  • MGI:1919843,
  • RIKEN cDNA 1200008O12 gene,
  • 1200008O12Rik,
  • Cep55,
  • RIKEN cDNA 2700032M20 gene,
  • 2700032M20Rik,
  • centrosomal protein 55

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