| Primary Identifier | MGI:96668 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 268345 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables transmembrane transporter binding activity. Acts upstream of or within action potential. Located in several cellular components, including neuronal cell body membrane; perikaryon; and synaptic membrane. Is expressed in several structures, including brain; genitourinary system; gut; spinal cord; and trigeminal nerve. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 103. Orthologous to human KCNC2 (potassium voltage-gated channel subfamily C member 2). PHENOTYPE: Mice homozygous for a knock-out allele display impaired fast spiking in cortical interneurons, distorted cortical rhythmic activity, enhanced susceptibility to seizures, increased anxiety in the open field, and abnormal sleep patterns. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
