Primary Identifier | MGI:6343190 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Abhd4 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 3 and 4 were replaced with a neomycin selection cassette. RT-PCR analysis confirmed loss of mRNA expression in brain and testis tissues from homozygous mutant mice. Lack of protein activity in mutant brains was confirmed by mass spectrometry (MS)-based activity-based protein profiling. |