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Allele : Abhd4<tm1Crv> abhydrolase domain containing 4; targeted mutation 1, Benjamin F Cravatt

Primary Identifier  MGI:6343190 Allele Type  Targeted
Attribute String  Null/knockout Gene  Abhd4
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 3 and 4 were replaced with a neomycin selection cassette. RT-PCR analysis confirmed loss of mRNA expression in brain and testis tissues from homozygous mutant mice. Lack of protein activity in mutant brains was confirmed by mass spectrometry (MS)-based activity-based protein profiling.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • ABHD4<->,
  • ABHD4<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele