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Publication : Assignment of the murine interferon sensitivity and cytoplasmic superoxide dismutase genes to chromosome 16.

First Author  Lin PF Year  1980
Journal  Science Volume  209
Issue  4453 Pages  285-7
PubMed ID  6155698 Mgi Jnum  J:6329
Mgi Id  MGI:54805 Doi  10.1126/science.6155698
Citation  Lin PF, et al. (1980) Assignment of the murine interferon sensitivity and cytoplasmic superoxide dismutase genes to chromosome 16. Science 209(4453):285-7
abstractText  Both hybrids of mouse and human microcells and whole cell hybrids generated by the fusion of primary mouse cells and SV40-transformed human fibroblasts were used to establish the syntenic association of the murine cytoplasmic superoxide dismutase and the interferon sensitivity genes on mouse chromosome 16. This assignment adds two new markers to chromosome 16 and provides another example of an evolutionarily conserved linkage. This finding also provides an animal model both for cellular responsiveness to interferon and for Down's syndrome.
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