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Protein Domain : EZH2, N-terminal domain

Primary Identifier  IPR040595 Type  Domain
Short Name  EZH2_N
description  Polycomb repressive complex 2 (PRC2) carries out the methylation of lysine 27 of histone H3, a hallmark of repressive chromatin. Three core subunits make up the catalytic core of PRC2; the SET domain containing EZH2, the zinc-finger containing SUZ12 and the WD40 repeat protein EED. The complex forms a compact arrangement of three lobes. This is the N-terminal domain of EZH2 [].

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0 Protein Domain Regions