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Allele : Kcnb1<em3Kea> potassium voltage gated channel, Shab-related subfamily, member 1; endonuclease-mediated mutation 3, Jennifer Kearney
Primary Identifier  MGI:6755225 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Kcnb1
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 editing was used to introduce nucleotide changes, including substitution of cysteine for arginine in codon 306 (CGC to TGC), and a silent change in codon 304 to disrupt an adjacent PAM site (ATC to ATT).
  • mutations:
  • Nucleotide substitutions
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