| Primary Identifier | IPR034999 | Type | Domain |
| Short Name | HuB_RRM2 |
| description | This entry represents the RNA recognition motif 2 (RRM2) of HuB. HuB (also known as ELAV-like protein 2 or Hel-N1) is one of the neuronal members of the Hu family []. The neuronal Hu proteins play important roles in neuronal differentiation, plasticity and memory. HuB is also expressed in gonads. It is up-regulated during neuronal differentiation of embryonic carcinoma P19 cells []. Like other Hu proteins, HuB contains three RNA recognition motifs (RRMs). RRM1 and RRM2 may cooperate in binding to an AU-rich RNA element (ARE). RRM3 may help to maintain the stability of the RNA-protein complex, and might also bind to poly(A) tails or be involved in protein-protein interactions []. |
