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Allele : Lamb3<tm1.1Hosc> laminin, beta 3; targeted mutation 1.1, Holm Schneider

Primary Identifier  MGI:5708309 Allele Type  Targeted
Gene  Lamb3 Transmission  Germline
Strain of Origin  (C57BL/6 x 129S4/SvJae)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  A 628G>A mutation was inserted in exon 7 and an FRT flanked neo cassette was introduced in intron 8 via homologous recombination. Flp mediated recombination removed the neo cassette. PCR analysis indicates the production of a shorter transcript with deletion of exon 7 resulting in a frameshift and premaure stop codon (p.V189NfsX8).
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • LAMB3 628G>A,
  • LAMB3 628G>A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele