Primary Identifier | IPR039912 | Type | Family |
Short Name | PNO1-like |
description | Pre-rRNA-processing protein PNO1 is also known as Partner of NOB1 and ribosomal RNA-processing protein 20. NOB1 is a nuclear protein that forms a complex with the 19S regulatory particle of the 26S proteasome and PNO1, acting as a chaperone to join the 20S proteasome with the 19S regulatory particle. The NOB1 complex is then degraded by the mature 26S proteasome []. PNO1 is also a component of the pre-ribosomal particle, and strains lacking PNO1 are defective in ribosomal RNA processing []. PNO1 remains a component of the SSU RRP complex, in which pre-40S subunits are left associated with a limited set of proteins []. PNO1 contains a K Homology domain. |