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Protein Coding Gene : Sgo2a shugoshin 2A
Primary Identifier  MGI:1098767 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  68549
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Acts upstream of or within several processes, including meiotic nuclear division; meiotic sister chromatid cohesion; and positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric. Located in kinetochore. Is expressed in nervous system and oocyte. Orthologous to human SGO2 (shugoshin 2).
PHENOTYPE: Mice homozygous for a null mutation display male and female infertility with abnormalities in meiosis but not in mitosis. [provided by MGI curators]
  • synonyms:
  • 5730576N04Rik,
  • shugoshin-like 2 (S. pombe),
  • MGI:2138513,
  • Sgo2a,
  • Tripin,
  • MGI:1917915,
  • AU018846,
  • Sgol2,
  • DNA segment, Chr 1, ERATO Doi 8, expressed,
  • RIKEN cDNA 1110007N04 gene,
  • MGI:1915799,
  • expressed sequence AU018846,
  • MGI:2138427,
  • AV008062,
  • D1Ertd8e,
  • RIKEN cDNA 5730576N04 gene,
  • shugoshin 2A,
  • 1110007N04Rik,
  • Sgol2a,
  • expressed sequence AV008062,
  • shugoshin-like 2a (S. pombe)
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Features --> Cross References

Genome

Sequence Feature Displayer

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2 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

18 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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