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Protein Coding Gene : Nuf2 NUF2, NDC80 kinetochore complex component
Primary Identifier  MGI:1914227 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  66977
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable microtubule binding activity. Predicted to be involved in kinetochore organization; mitotic spindle organization; and nuclear chromosome segregation. Predicted to act upstream of or within cell division. Predicted to be located in cytosol; kinetochore; and nucleoplasm. Predicted to be part of Ndc80 complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma and pancreatic cancer. Orthologous to human NUF2 (NUF2 component of NDC80 kinetochore complex).
  • synonyms:
  • C85691,
  • RIKEN cDNA 2410003C07 gene,
  • NUF2, NDC80 kinetochore complex component,
  • MGI:2138707,
  • 2410003C07Rik,
  • AU044112,
  • Nuf2,
  • Cdca1,
  • Nuf2R,
  • MGI:2138503,
  • cell division cycle associated 1,
  • expressed sequence C85691,
  • expressed sequence AU044112
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Features --> Cross References

Genome

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0 Canonical

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2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

18 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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