| Primary Identifier | MGI:106014 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 18221 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable unfolded protein binding activity. Predicted to be involved in several processes, including mitotic metaphase chromosome alignment; mitotic spindle organization; and protein folding. Predicted to act upstream of or within cell division. Predicted to be located in cytosol; midbody; and mitotic spindle. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human NUDC (nuclear distribution C, dynein complex regulator). PHENOTYPE: Rod photoreceptor-specific knock-out mice show complete rod photoreceptor degeneration and photopic and scotopic dysfunction, with glial inflammation, abnormal trafficking of and loss of rhodopsin, and mislocalization of mitochondria. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
