| Primary Identifier | MGI:5007645 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Myh6-Tpm1*E180G)57Dfw |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| description | Four lines, 33, 52, 57, and 58 were made (J:172340). |
| molecularNote | This transgene consists of the murine alpha-myosin heavy chain cardiac-specific promoter ligated to the 5' end of the mouse alpha-tropomyosin with a single point mutation (GAG to GGG) corresponding to a glycine substitution for a glutamic acid at codon 180. This region interacts with troponin T. Quantification of the transgene demonstrates that copy number in line 57 is 22 copies. |
