Primary Identifier | MGI:2386551 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Nes-cre)3Wme |
Strain of Origin | (C57BL/6 x CBA)F2 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The transgenic construct contained a nestin promoter followed by cre recombinase sequence adjoined to a nuclear localization signal. Intron 2 of the nestin gene was included downstream of a polyadenylation signal. While the endogenous nestin promoter is CNS-specific, Southern blot analysis showed the ubiquitous expression of cre in transgenic mice. |