Primary Identifier | IPR030525 | Type | Family |
Short Name | DLGAP2 |
description | Disks large-associated protein 2 (DLGAP2, SAPAP2) belongs to the SAPAP family. It is involved in neuronal synaptic function []and has been linked to autism []and schizophrenia [].SAPAP family members are PSD-95/SAP90-associated proteins localised at postsynaptic density []. Postsynaptic density (PSD) is a specialised submembranous structure within which synaptic membrane proteins are linked to cytoskeleton and signalling proteins. PSD-95/SAP90 is one of the major components of PSD, and functions as a scaffold protein for various ion channels and associated signalling molecules. |