| First Author | Lu W | Year | 2013 |
| Journal | Neuron | Volume | 78 |
| Issue | 3 | Pages | 433-9 |
| PubMed ID | 23664612 | Mgi Jnum | J:259662 |
| Mgi Id | MGI:6147902 | Doi | 10.1016/j.neuron.2013.02.030 |
| Citation | Lu W, et al. (2013) The cell-autonomous role of excitatory synaptic transmission in the regulation of neuronal structure and function. Neuron 78(3):433-9 |
| abstractText | The cell-autonomous role of synaptic transmission in the regulation of neuronal structural and electrical properties is unclear. We have now employed a genetic approach to eliminate glutamatergic synaptic transmission onto individual CA1 pyramidal neurons in a mosaic fashion in vivo. Surprisingly, while electrical properties are profoundly affected in these neurons, as well as inhibitory synaptic transmission, we found little perturbation of neuronal morphology, demonstrating a functional segregation of excitatory synaptic transmission from neuronal morphological development. |
