First Author | Takezawa R | Year | 1993 |
Journal | Biochim Biophys Acta | Volume | 1172 |
Issue | 1-2 | Pages | 220-2 |
PubMed ID | 8439566 | Mgi Jnum | J:4118 |
Mgi Id | MGI:52619 | Doi | 10.1016/0167-4781(93)90300-3 |
Citation | Takezawa R, et al. (1993) Determination of mouse major asialoglycoprotein receptor cDNA sequence. Biochim Biophys Acta 1172(1-2):220-2 |
abstractText | Hepatic lectins (asialoglycoprotein receptors) specifically recognize galactose-terminated glycoproteins and mediate endocytosis of these molecules. We now report the cloning and sequence of a cDNA encoding murine asialoglycoprotein receptor. It shows high homology with rat and human major receptor forms designated RHL-1 and HHL-1, respectively. They have many conserved regions, such as a transmembrane region, carbohydrate additional region and carbohydrate related region. According to the homology analysis, we concluded that the clone encodes the mouse major asialoglycoprotein receptor (MHL-1). |