| First Author | Lin Q | Year | 2011 |
| Journal | Nat Neurosci | Volume | 14 |
| Issue | 9 | Pages | 1115-7 |
| PubMed ID | 21841775 | Mgi Jnum | J:179785 |
| Mgi Id | MGI:5303046 | Doi | 10.1038/nn.2891 |
| Citation | Lin Q, et al. (2011) The brain-specific microRNA miR-128b regulates the formation of fear-extinction memory. Nat Neurosci 14(9):1115-7 |
| abstractText | MicroRNAs are small non-coding RNAs that mediate post-transcriptional gene silencing. Fear-extinction learning in C57/Bl6J mice led to increased expression of the brain-specific microRNA miR-128b, which disrupted stability of several plasticity-related target genes and regulated formation of fear-extinction memory. Increased miR-128b activity may therefore facilitate the transition from retrieval of the original fear memory toward the formation of a new fear-extinction memory. |
