Primary Identifier | MGI:3033142 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 211578 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in genitourinary system; nervous system; and skin. Used to study dilated cardiomyopathy. Orthologous to human MRGPRD (MAS related GPR family member D). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased sensitivity to cold, heat, and mechanical stimuli. Mice for another null allele exhibit dilated cardiomypathy and cardiac dysfunction. [provided by MGI curators] |