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Protein Domain : NDT80 DNA-binding domain

Primary Identifier  IPR024061 Type  Domain
Short Name  NDT80_DNA-bd_dom
description  The NDT80 DNA-binding domain is found in the following proteins, which might all be involved in sensing nutritional status []:Yeast meiosis-specific transcription factor NDT80, the key transcription factor that ultimately allows the continuation of meiosis after the successful completion of recombination.Emericella nidulans phoG (xprG), a transcriptional activator involved in the response to nutrient limitation.Emericella nidulans putative uncharacterised protein AN6015.2.Neurospora crassa transcription factor vib-1, involved in the control of heterokaryon incompatibility.Neurospora crassa related to acid phosphatase NCU04729.Neurospora crassa related to meiosis-specific protein NDT80 NCU09915.The proteolytically resistant core NDT80 DNA-binding domain reveals a central β-sandwich characteristic of an s-type Ig fold. The β-sandwich contains a three-stranded sheet composed of strands a, b and e, packed against a four-stranded sheet composed of strands c', c, f and g. Each sheet of the β-sandwich contains an additional β-strand, as well as a variety of peripheral secondary structure elements. The NDT80 DNA-binding domain contains an N-terminal extension, which consists of a β-hairpin and a loop [].

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4 Protein Domain Regions