| Primary Identifier | MGI:99926 | Organism | mouse, laboratory |
| Chromosome | MT | NCBI Gene Number | 17706 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Predicted to act upstream of or within ATP biosynthetic process and proton transmembrane transport. Located in mitochondrion. Is expressed in heart; liver; and metanephros. Human ortholog(s) of this gene implicated in multiple sclerosis and urinary bladder cancer. Orthologous to human MT-ATP8 (mitochondrially encoded ATP synthase membrane subunit 8). PHENOTYPE: Mice carrying homoplastic mtDNAs with a single point mutation in this gene exhibit increased anxiety-like behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
