Primary Identifier | MGI:1330826 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 11981 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable ATPase-coupled intramembrane lipid transporter activity and protease binding activity. Involved in neuron projection morphogenesis. Located in early endosome and late endosome. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system gland; peripheral nervous system; and retina. Orthologous to human ATP9A (ATPase phospholipid transporting 9A (putative)). PHENOTYPE: Homozygous null mice show decreased muscle strength, learning and memory deficits, hyperkinetic movement disorder, abnormal neurite morphology and impaired synaptic transmission in the motor cortex and hippocampus. [provided by MGI curators] |