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Publication : Cranial and related sensorimotor impairments in rodent models of Parkinson's disease.

First Author  Fleming SM Year  2012
Journal  Behav Brain Res Volume  231
Issue  2 Pages  317-22
PubMed ID  22394540 Mgi Jnum  J:185469
Mgi Id  MGI:5428820 Doi  10.1016/j.bbr.2012.02.034
Citation  Fleming SM, et al. (2012) Cranial and related sensorimotor impairments in rodent models of Parkinson's disease. Behav Brain Res 231(2):317-22
abstractText  In Parkinson's disease both limb and cranial sensorimotor functions are impaired, leading to a profound diminished quality of life for many patients. Toxin and genetic animal models of Parkinson's disease are likely essential for understanding the pathology associated with these impairments as well as for the development and testing of potential therapeutics. Here we describe useful novel and established behavioral outcome measures for assessing limb and cranial sensorimotor functions in toxin and genetic models of parkinsonism in rats and mice.
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