Primary Identifier | MGI:3577071 | Allele Type | QTL |
Gene | Scc12 | Inheritance Mode | Not Specified |
Strain of Origin | STS/A | Is Recombinase | false |
Is Wild Type | false |
description | Animals heterozygous at Scc12 and homozygous for STS/A-derived alleles at Ssc5 exhibit the greatest susceptibility to AOM-induced colon tumors. Scc12 also shows suggestive interaction with Scc3 on chromosome 1. |
molecularNote | Heteozygosity for this allele in conjunction with Scc5 confers colon tumor susceptibility. |